Difference between revisions of "Multi-year optimization of malaria intervention: a mathematical model"

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Revision as of 06:18, 17 September 2016

by: Harry J. Dudley, Abhishek Goenka, Cesar J. Orellana and Susan E. Martonosi

Abstract

Background

Malaria is a mosquito-borne, lethal disease that affects millions and kills hundreds of thousands of people each year, mostly children. There is an increasing need for models of malaria control. In this paper, a model is developed for allocating malaria interventions across geographic regions and time, subject to budget constraints, with the aim of minimizing the number of person-days of malaria infection. Methods

The model considers a range of several conditions: climatic characteristics, treatment efficacy, distribution costs, and treatment coverage. An expanded susceptible-infected-recovered compartment model for the disease dynamics is coupled with an integer linear programming model for selecting the disease interventions. The model produces an intervention plan for all regions, identifying which combination of interventions, with which level of coverage, to use in each region and year in a 5-year planning horizon.


Link to Website:https://malariajournal.biomedcentral.com/articles/10.1186/s12936-016-1182-0


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